Nucleofill Strong Biorevitalizant with Polynucleotides 1.5 ml

Technical specifications

  • Packaging: 1 syringe of 1.5 ml with needles

  • Active ingredient: polynucleotides 25 mg/ml (2.5%)

  • Hyaluronic acid concentration: none

  • Volume: 1.5 ml

  • Country of origin: Italy

  • Needles: 30G 1/2 (2 pcs.)

65.00 €

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Main features

Description

Key features

Nucleofill Strong by the Italian brand Promoitalia is an advanced biorevitalizant with a unique mechanism of biostimulation. It activates receptors CD39 and CD40, stimulating type I collagen synthesis and transforming fibroblasts into myofibroblasts. As a result, PDRN polynucleotides integrate essential components (glycosaminoglycans, proteins, fibrils, glycoproteins) into the dermis, supporting natural tissue regeneration.

The gel is viscous, homogeneous, and pyrogen-free, containing low-molecular polynucleotides derived from salmon fish milt. These molecules can integrate into damaged DNA segments and trigger repair processes.

Nucleofill Strong works on three levels:

  • lifting — tissue densification and improved firmness;

  • antioxidant protection — neutralization of free radicals;

  • deep hydration — long-lasting dermal matrix moisturization.

The product is safe, naturally restores skin structure, and gives it radiance, freshness, and a youthful look.

Areas of Application

Nucleofill Strong enhances bioregeneration in both deep layers (fat and bone tissue) and the dermis. Effective in the following areas:

  • face,

  • neck,

  • décolleté,

  • hands.

Application Protocol

Injections are performed intradermally using a needle or cannula. The technique (papular, fan, retrograde-linear, or meso-threading) is chosen by the specialist depending on skin needs. The procedure is almost painless, with only slight tingling possible.
Recommended course: 4 sessions at 2–4 week intervals.

Results

After the course with Nucleofill Strong, the skin:

  • improves in tone;

  • shows reduction of fine lines and softening of deeper wrinkles;

  • becomes denser and firmer;

  • achieves higher hydration levels;

  • looks refreshed, rejuvenated, and radiant.

Additional information
Brand (Biorevitalization)

Nucleofill

Country (Biorevitalization)

Italy

Indications (Biorevitalization)

Cheek Wrinkles

,

Fine Lines

,

Neck Wrinkles

,

Skin Laxity

,

Skin Sagging

Composition Features (Biorevitalization)

,

Application Areas (Biorevitalization)

,

,

,

Hyaluronic Acid Concentration

Duration of Action

Dermal Layers

Volume (ml) (Biorevitalization)

1.5 ml

About brand

Nucleofill polynucleotides by Promoitalia — buy for aesthetic professionals

Nucleofill is a polynucleotide skin booster range by the Italian company Promoitalia. The products contain no hyaluronic acid and are used to restore skin density and elasticity. Our catalogue offers two concentrations in 1.5 ml syringes with 30G needles. Shipping to EU countries and Ukraine.

Products in our catalogue

  • Nucleofill Medium — 20 mg/ml polynucleotides: face, neck, décolleté, hands.
  • Nucleofill Strong — 25 mg/ml polynucleotides: marked laxity, scars, acne scarring, stretch marks.

Medium suits skin-quality courses, Strong more pronounced changes. Other Nucleofill products (Medium Plus, Soft Plus Eyes) are on the Promoitalia brand page and in polynucleotide skin boosters.

What is the difference between Nucleofill Medium and Strong?

Polynucleotide concentration: Medium 20 mg/ml, Strong 25 mg/ml. Strong is chosen for more pronounced skin changes.

Does Nucleofill contain hyaluronic acid?

No, Nucleofill Medium and Strong contain polynucleotides only.

What is in the box?

One 1.5 ml syringe and two 30G needles.

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